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英文名称：CDC23 Antigen (Recombinant Protein)
别 名： cell division cycle 23; APC8; CUT23; ANAPC8
储 存： 冷冻（-20℃）
相关类别：抗原
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Fusion protein corresponding to a region derived from 398-597 amino acids of human CDC23 |
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Full name: |
cell division cycle 23 |
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Synonyms: |
APC8; CUT23; ANAPC8 |
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Swissprot: |
Q9UJX2 |
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Gene Accession: |
BC017713 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. |
