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英文名称: CDC42EP2 Antigen (Recombinant Protein)
别 名: CDC42 effector protein 2; CEP2; BORG1
储 存: 冷冻(-20℃)
相关类别: 抗原
Fusion protein corresponding to a region derived from 2-210 amino acids of human CDC42EP2 |
Full name: |
CDC42 effector protein 2 |
Synonyms: |
CEP2; BORG1 |
Swissprot: |
O14613 |
Gene Accession: |
BC022337 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. |