兔抗SHPK多克隆抗体

Background:

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Applications:

ELISA, WB, IHC

Name of antibody:

SHPK

Immunogen:

Fusion protein of human SHPK

Full name:

sedoheptulokinase

Synonyms:

SHK; CARKL

SwissProt:

Q9UHJ6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer;

IHC Recommend dilution:

40-200

WB Predicted band size:

51 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

500-2000