兔抗PDE1B多克隆抗体

Background:

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

WB

Name of antibody:

PDE1B

Immunogen:

Fusion protein of human PDE1B

Full name:

phosphodiesterase 1B, calmodulin-dependent

Synonyms：

PDE1B1; PDES1B

SwissProt:

Q01064

WB Predicted band size:

61 kDa

WB Positive control:

NCL and THP1 cells, mouse brain and spleen tissue, spinal cord tissue

WB Recommended dilution:

500-2000