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技术规格
Background:
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204])
Applications:
WB
Name of antibody:
RAPGEF5
Immunogen:
Synthesized peptide derived from internal of human RAPGEF5.
Full name:
Rap guanine nucleotide exchange factor (GEF) 5
Synonyms:
GFR; REPAC; MR-GEF
SwissProt:
Q92565
WB Predicted band size:
68 kDa
WB Positive control:
RAW264.7 cells lysate
WB Recommended dilution:
500-3000