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英文 名称: Anti-TPMT rabbit polyclonal antibody
别 名: thiopurine S-methyltransferase; TPMTD
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: TPMT
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.
Applications:
ELISA, IHC
Name of antibody:
TPMT
Immunogen:
Fusion protein of human TPMT
Full name:
thiopurine S-methyltransferase
Synonyms:
TPMTD
SwissProt:
P51580
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human cervical cancer
IHC Recommend dilution:
40-200