兔抗TH(Ab-19)多克隆抗体

Background:

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Applications:

WB, IHC, IF

Name of antibody:

TH(Ab-19)

Immunogen:

Synthesized non-phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 19 (A-V-S(p)-E-Q).

Full name:

tyrosine hydroxylase

Synonyms：

TYH; DYT14; DYT5b

SwissProt:

Q2M3B4

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

59 kDa

WB Positive control:

NIH/3T3 cells treated with Forskolin (40nM, 30min) lysate

WB Recommended dilution:

500-3000

IF positive control:

Huvec cells

IF Recommend dilution:

100-500