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技术规格
Background:
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.
Applications:
ELISA, WB
Name of antibody:
SIRT2
Immunogen:
Fusion protein of human SIRT2
Full name:
Sirtuin 2
Synonyms:
SIR2; SIR2L; SIR2L2
SwissProt:
Q8IXJ6
ELISA Recommended dilution:
1000-2000
WB Predicted band size:
43 kDa
WB Positive control:
Mouse heart tissue
WB Recommended dilution:
200-1000