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技术规格
Background:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Applications:
ELISA, IHC
Name of antibody:
RAMP3
Immunogen:
Fusion protein of human RAMP3
Full name:
receptor (G protein-coupled) activity modifying protein 3
SwissProt:
O60896
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human ovarian cancer and Human thyroid cancer
IHC Recommend dilution:
50-200