手机扫码访问本站
微信咨询
英文名称: Anti-TNFRSF10C rabbit polyclonal antibody
别 名: LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
抗 原: TNFRSF10C
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Applications:
ELISA, IHC
Name of antibody:
TNFRSF10C
Immunogen:
Fusion protein of human TNFRSF10C
Full name:
tumor necrosis factor receptor superfamily member 10c
Synonyms:
LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
SwissProt:
O14798
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and human lung cancer
IHC Recommend dilution:
25-100