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技术规格
Background:
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.
Applications:
ELISA, IHC
Name of antibody:
SELL
Immunogen:
Synthetic peptide of human SELL
Full name:
selectin L
Synonyms:
TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
SwissProt:
P14151
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human esophagus cancer and Human thyroid cancer
IHC Recommend dilution:
20-100