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Background:
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
RAB23
Immunogen:
Fusion protein of human RAB23
Full name:
RAB23, member RAS oncogene family
Synonyms:
HSPC137
SwissProt:
Q9ULC3
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer and Human tonsil
IHC Recommend dilution:
50-200