兔抗PDZK1多克隆抗体

Background:

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma.

Applications:

WB, IHC

Name of antibody:

PDZK1

Immunogen:

Fusion protein of human PDZK1

Full name:

PDZ domain containing 1

Synonyms：

CAP70; CLAMP; PDZD1; NHERF3; NHERF-3

SwissProt:

Q5T2W1

IHC positive control:

Human prostate cancer and Human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

57 kDa

WB Positive control:

Mouse kidney tissue

WB Recommended dilution:

200-1000