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英文名称: Anti-TRAF3 rabbit polyclonal antibody
别 名: CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: TRAF3
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Applications:
ELISA, WB, IHC
Name of antibody:
TRAF3
Immunogen:
Synthetic peptide of human TRAF3
Full name:
TNF receptor-associated factor 3
Synonyms:
CAP1, LAP1, CAP-1, CRAF1, IIAE5, CD40bp
SwissProt:
Q13114
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human tonsil
IHC Recommend dilution:
25-100
WB Predicted band size:
64 kDa
WB Positive control:
Mouse kidney tissue
WB Recommended dilution:
200-1000