兔抗NFATC1多克隆抗体

Background:

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Applications:

ELISA, IHC

Name of antibody:

NFATC1

Immunogen:

Fusion protein of human NFATC1

Full name:

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Synonyms：

NFAT2, NFATc, NF-ATC

SwissProt:

O95644

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and Human cervical cancer

IHC Recommend dilution:

25-100