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英文 名称: Anti-TRAF1 rabbit polyclonal antibody
别 名: EBI6; MGC:10353
抗 原: TRAF1
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.
Applications:
ELISA, WB, IHC
Name of antibody:
TRAF1
Immunogen:
Fusion protein of human TRAF1
Full name:
TNF receptor-associated factor 1
Synonyms:
EBI6; MGC:10353
SwissProt:
Q13077
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human colon cancer and human cervical cancer
IHC Recommend dilution:
15-50
WB Predicted band size:
46 kDa
WB Positive control:
Human lymphoma tissue
WB Recommended dilution:
200-1000