兔抗NFKBID多克隆抗体

Background:

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

Applications:

ELISA, WB, IHC

Name of antibody:

NFKBID

Immunogen:

Fusion protein of human NFKBID

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

Synonyms：

TA-NFKBH, IkappaBNS

SwissProt:

Q8NI38

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human colon cancer and Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

33 kDa

WB Positive control:

RAW264.7 cells

WB Recommended dilution:

200-1000