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技术规格
Background:
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [
Applications:
WB, IF
Name of antibody:
RPS4X
Immunogen:
Synthesized peptide derived from internal of human RPS4X.
Full name:
ribosomal protein S4, X-linked
Synonyms:
S4; CCG2; RPS4; SCAR; SCR10; DXS306
SwissProt:
P62701
WB Predicted band size:
30 kDa
WB Positive control:
COLO cells and Hela cells lysates
WB Recommended dilution:
500-3000
IF positive control:
Huvec cells
IF Recommend dilution:
100-500