兔抗NR3C1(Phospho-Ser226)多克隆抗体

Background:

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance.

Applications:

WB

Name of antibody:

NR3C1(Phospho-Ser226)

Immunogen:

Peptide sequence around phosphorylation site of serine 226 (L-L-S(p)-P-L) derived from Human GR.

Full name:

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Synonyms：

GR; GCR; GRL; GCCR; GCRST

SwissProt:

P04150

WB Predicted band size:

86 kDa

WB Positive control:

Jurkat cells lysates treated with EGF

WB Recommended dilution:

500-1000