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Background:
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:
ELISA, WB
Name of antibody:
SPI1
Immunogen:
Synthetic peptide of human SPI1
Full name:
Spi-1 proto-oncogene
Synonyms:
OF; PU.1; SFPI1; SPI-1; SPI-A
SwissProt:
P17947
ELISA Recommended dilution:
5000-10000
WB Predicted band size:
31 kDa
WB Positive control:
Mouse liver tissue lysate
WB Recommended dilution:
500-2000