手机扫码访问本站
微信咨询
技术规格
Background:
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Applications:
ELISA, WB, IHC
Name of antibody:
SOCS6
Immunogen:
Fusion protein of human SOCS6
Full name:
suppressor of cytokine signaling 6
Synonyms:
CIS4; SSI4; CIS-4; SOCS4; STAI4; SOCS-4; SOCS-6; STATI4; HSPC060
SwissProt:
O14544
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human liver cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
60 kDa
WB Positive control:
Human placenta tissue lysate
WB Recommended dilution:
200-1000