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技术规格
Background:
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Applications:
WB
Name of antibody:
SP100
Immunogen:
Synthesized peptide derived from Internal of human SP100.
Full name:
SP100 nuclear antigen
Synonyms:
lysp100b
SwissProt:
P23497
WB Predicted band size:
100 kDa
WB Positive control:
HT29 cells lysate
WB Recommended dilution:
500-3000