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中文名称： GCNT2 抗原（重组蛋白）
英文名称： GCNT2 Antigen (Recombinant Protein)
别 名： glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRC
相关类别： 抗原
储 存：冷冻（-20℃）
概述
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Fusion protein corresponding to a region derived from 203-402 amino acids of human GCNT2 |
技术规格
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Full name: |
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
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Synonyms: |
II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2 |
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Swissprot: |
Q8N0V5 |
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Gene Accession: |
BC130524 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. |
